Gapped acidosis12/24/2023 ![]() Here were Petrarca’s initial recommendations: Petrarca booked a scheduled clinical consultation with Jasmyne Brown, ND of GPL to collaborate on the initial and follow-up OAT findings.ĭuring consultation with the patient where the initial OAT findings were revealed, Petrarca learned that Lori’s house was built over a creek and had cabinets that could be damp or moldy. To help Lori mend emotionally, Petrarca also encouraged her to spend as much time as possible with supportive relationships in her life, including friends, her dog, and riding her horses and encouraged Lori to continue building a new wellness treatment team.Īt the turn of the year, Lori was able to leave her primary health care doctor at Kaiser, and initiate care with a provider who she could choose that accepts Medicare patients. Petrarca helped Lori support her health through leveraging the MATRIX – which included supplements to repair her gut, and support mitochondria to help her regain energy because Lori’s current diet was insufficient in nutrients as demonstrated in the OAT findings. Fortunately, Lori was also starting work with a mental health therapist to assist with these goals. Petrarca then advised Lori to begin focusing on quality rest and relationships to assist her mind, body and spirit during the grieving process. Petrarca focused on the core modifiable lifestyle variables at the bottom of the IFM MATRIX, which include stress, sleep/restoration, nutrition, relationships, and exercise/movement. Lori worried that the higher level of oxalates on page three of her OAT may lead to future kidney stones and was concerned about the implications. The OAT also showed indications of microbial and cellular stress to the mitochondria and high oxalates. Lori’s intake OAT revealed yeast, fungal, bacterial issues, specifically marker 54 showed evidence that yeast and mold were thriving inside her body. The below sample reports shows what the OAT revealed to Petrarca initially and during a six-month follow-up. ![]() ![]() To gather more data, Petrarca ordered a Comprehensive Stool Analysis, Organic Acid Test, and Advanced Lipid Panel. Lori shared her CBC bloodwork with Petrarca, which revealed elevated RBC and elevated Platelets – consistent with the diagnosis of Polycythemia Vera (PV), which is typically treated with Hydroxyurea, an oral chemotherapy agent – a medication that at the age of 65 terrified Lori.Ī Battery of Diagnostics Reveal Needed Answers Lori was hopeful that Petrarca’s 25 years of experience in emergency nursing and more than 10 years of experience treating patients with functional medicine would be the right blend of experience to assist her with moving forward.ĭuring their initial consult, Petrarca learned that Lori was grief stricken, depressed, and struggling with numerous imbalances including profuse itching and ocular migraines. OM, IFMCP, owner of BiaoHealth in San Francisco, California. One of Lori’s best friends referred her to work with a functional medicine provider, Amy Petrarca, MS, RN, L Ac, Dipl. When her father passed away, Lori decided to seek help for a new and threatening diagnosis of Polycythemia Vera, which she found terrifying. Her current clinical symptoms at that time included anxiety, depression, poor concentration, fatigue, joint pain, and decreased appetite. Sometimes hidden ailments not uncovered by traditional physicians can only be revealed by tried and true tests such as the Organic Acids Test (OAT) and a comprehensive stool analysis.Īfter years of caregiving for her father, Lori’s emotional, physical, and spiritual life had all but flatlined. He also discusses the utility of specific immune and neurological testing. He uses Organic Acid Test (OAT) results as well as MycoTOX Profile results to illustrate possible responses to mycotoxins such as trichothecenes, aflatoxins, zearalenone, and ochratoxins. Neuenschwander mentions the myriad patient symptoms that can result from toxic processes instigated by mycotoxin exposure: psychiatric and cognitive symptoms, any chronic syndrome, respiratory symptoms, as well as POTS and other vagal symptoms. Patients with a chronic toxic load may develop MCAS and other indications of immune upregulation.ĭr. Eventually, thyroid function is thrown off, and histamine increases. The cell resorts to aerobic glycolysis, oxidative stress and glutamate level increase, and glutathione is diverted, vitamin D production drops, and methylation reactions are impaired. The presence of ATP outside the cell is part of cellular danger signaling, along with the appearance of various caspase enzymes at several points in the apoptosis process. The full presentation includes the role of mitochondria, thought of primarily as energy producers, but which are very involved in the cellular response to stress.
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